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” He and Munakata feel that gradual variations in the way in which the DNA is saved could lead to a lack of fertility as Gals age. If that's so, their investigation could pave the way for improved treatment method and prognosis of fertility complications.

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Munakata and Namekawa will compare mice with standard and mutated variations on the chromatin remodeler. As the mice grow and experienced, they can notice whether or not the existence or absence of the protein triggers variances in the arrangement of DNA spools within the animals’ oocytes. And they will monitor irrespective of whether this, consequently, alters the pattern of gene expression over time.

Big protein machines, called chromatin remodelers, can change the positions of spools up and down the DNA thread, thus facilitating the expression — or silencing — of Many genes.

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